Skip to main content

Science

Academic & Scientific Experts Confirm Safety & Efficacy of Low Calorie Sweeteners (LCS)

  • LCS can help reduce calorie intake and assist weight/ diabetes management when used in place of sugar1
  • LCS have no adverse effect on blood glucose and insulin regulation (HbA1c, fasting and post-prandial glucose and insulin levels) in people with and without diabetes1

FAQs About Splenda®

Aren’t All Sweeteners The Same?

No! Splenda Brand Sweeteners have been voted best-tasting by consumers and are the #1 Recommended Sweetener Brand by healthcare professionals.*

Splenda Stevia is made from the best tasting part of non-GMO stevia plant leaves and erythritol — two plant based ingredients.

Splenda Original is made with sucralose from a process that starts with sugar. It does NOT contain aspartame or saccharin.

Taste Influences Food Choices, Eating Behaviors, and Food Intake

Consumers prefer Splenda Brand Sweeteners

Learn More
Scientific Publications Summary

Splenda Scientific Summmary

The safety and efficacy of low and zero calorie sweeteners (LNCS) have been researched for decades. This summary provides a selection of recent and well-designed scientific studies, articles and position statements in addition to a quick summary of the evaluation and regulatory review of LNCS in the U.S. and globally.

1 Ashwell, M., et. al. (2020). Nutr Res Rev. 2020 Jan 13:1-10. doi: 10.1017/S0954422419000283 *Among healthcare professionals clinically treating patients.

FAQs: 1. Roberts, A. (2016). The safety and regulatory process for low-calorie sweeteners in the United States. Physiology & Behavior. 164, Part B, 439-444. 2. (2019) Low Calorie Sweeteners and Sweet Taste. Calorie Control Council. Retrieved from: https://caloriecontrol.org/sweet-taste/ 3. When used in place of sugar; Rogers PJ, Hogenkamp PS, de Graaf C, et al. (2016) Does low-energy sweetener consumption affect energy intake and body weight? A systematic review, including meta-analyses, of the evidence from human and animal studies. Int J of Obes 40(3), 381-394. 4. Johnston C, Stevens B, Foreyt J et al. (2013) The Role of Low-calorie Sweeteners in Diabetes. Eur Endocrinology 9(2); 96-98. 5. Rogers PJ. The role of low-calorie sweeteners in the prevention and management of overweight and obesity: evidence v. conjecture. Proc Nutr Soc, 2017 Nov;23:1-9. 6. Lobach, A. R., Roberts, A., & Rowland, I. R. (2018). Assessing the in vivo data on low/no-calorie sweeteners and the gut microbiota. Food and Chemical Toxicology, 124, 385-399.